(±) -1,2-Propanediol-d8

(±) -1,2-Propanediol-d8 is the deuterium labeled (±) -1,2-Propanediol. (±) -1,2-Propanediol (1,2- (RS) -Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents[1][2].

Product Specifications

CAS Number

[80156-55-4]

Product Name Alternative

1,2- (RS) -Propanediol-d8; 1,2-Propylene glycol-d8; Propylene glycol-d8

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Neurological Disease

Purity

99.55

Solubility

10 mM in DMSO

Smiles

[2H]OC([2H])([2H])C(O[2H])([2H])C([2H])([2H])[2H]

Molecular Formula

C3D8O2

Molecular Weight

84.14

Precautions

H302, H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]De Cock RF, et al. Low but inducible contribution of renal elimination to clearance of propylene glycol in preterm and term neonates. Ther Drug Monit. 2014 Jun;36 (3) :278-87.