FDPS, Human (His)

FDPS Protein, a key enzyme in isoprenoid biosynthesis, catalyzes the formation of farnesyl diphosphate (FPP). FPP is a precursor for essential metabolites like sterols, dolichols, carotenoids, and ubiquinones. It also serves as a substrate for protein farnesylation and geranylgeranylation. FDPS sequentially condenses isopentenyl pyrophosphate with dimethylallyl pyrophosphate and then with geranylpyrophosphate to produce farnesyl pyrophosphate. FDPS Protein, Human (His) is the recombinant human-derived FDPS protein, expressed by E. coli , with N-His labeled tag. The total length of FDPS Protein, Human (His) is 353 a.a., with molecular weight of ~41 kDa.

MNGDQNSDVY AQEKQDFVQH FSQIVRVLTE DEMGHPEIGD AIARLKEVLE YNAIGGKYNR GLTVVVAFRE LVEPRKQDAD SLQRAWTVGW CVELLQAFFL VADDIMDSSL TRRGQICWYQ KPGVGLDAIN DANLLEACIY RLLKLYCREQ PYYLNLIELF LQSSYQTEIG QTLDLLTAPQ GNVDLVRFTE KRYKSIVKYK TAFYSFYLPI AAAMYMAGID GEKEHANAKK ILLEMGEFFQ IQDDYLDLFG DPSVTGKIGT DIQDNKCSWL VVQCLQRATP EQYQILKENY GQKEAEKVAR VKALYEELDL PAVFLQYEED SYSHIMALIE QYAAPLPPAV FLGLARKIYK RRK