Pimaric acid
Pimaric acid is a resin acid that has been found in A. cordata and various pines. Pimaric acid exerts anticancer effects via endoplasmic reticulum stress, caspase-dependent apoptosis, cell cycle arrest, and inhibition of cell migration in human ovarian cancer cells. Pimaric acid reduces mRNA expression, protein levels, and promoter activity of matrix metalloproteinase-9 (MMP-9) in TNF-α-stimulated human aortic smooth muscle cells (HASMCs) [1][2][3].
Product Specifications
CAS Number
127-27-5
UNSPSC
12352211
Target
Apoptosis; MMP; NF-κB; p38 MAPK
Type
Reference compound
Related Pathways
Apoptosis; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/pimaric-acid.html
Purity
98.76
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@]1(C)CCC[C@]2(C)[C@@]3([H])CC[C@@](C)(C=C)C=C3CC[C@@]12[H])O
Molecular Formula
C20H30O2
Molecular Weight
302.45
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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