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Tubulin inhibitor 43

Selected Variant

HY-160854

Size: 1 Each

Tubulin inhibitor 43 (Compound 29) has significant antitumor activity. Tubulin inhibitor 43 inhibits the proliferation and growth of cancer cells by inhibiting the activity of β-microtubulin, and finally induces apoptosis[1].

Product Specifications

CAS Number

1541208-02-9

UNSPSC

12352005

Target

Apoptosis; Microtubule/Tubulin

Type

Reference compound

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tubulin-inhibitor-43.html

Solubility

10 mM in DMSO

Smiles

O=C1N(C2=CC(OC)=C(C(OC)=C2)OC)[C@@H](C3=CC(O)=C(C=C3)OC)C1=C

Molecular Formula

C20H21NO6

Molecular Weight

371.38

References & Citations

[1]Zhou P, et al.Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents. Eur J Med Chem. 2018 Jan 20;144:817-842.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Price

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