Tubulin inhibitor 43
Selected Variant
HY-160854
Size: 1 Each
Tubulin inhibitor 43 (Compound 29) has significant antitumor activity. Tubulin inhibitor 43 inhibits the proliferation and growth of cancer cells by inhibiting the activity of β-microtubulin, and finally induces apoptosis[1].
Product Specifications
CAS Number
1541208-02-9
UNSPSC
12352005
Target
Apoptosis; Microtubule/Tubulin
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-inhibitor-43.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C2=CC(OC)=C(C(OC)=C2)OC)[C@@H](C3=CC(O)=C(C=C3)OC)C1=C
Molecular Formula
C20H21NO6
Molecular Weight
371.38
References & Citations
[1]Zhou P, et al.Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents. Eur J Med Chem. 2018 Jan 20;144:817-842.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Price
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