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VTSEGAGLQLQK-13C6,15N2 (TFA)

Product Specifications

UNSPSC Description

VTSEGAGLQLQK-13C6,15N2 (TFA) is the 13C- and 15N-labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA), which can be used to bind anti-drug antibodies in plasma and quantitatively analyze the therapeutic effect[1][2].

Target Antigen

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/vtsegaglqlqk-13c6-15n2-tfa.html

Solubility

10 mM in DMSO

Smiles

O=C(C(F)(F)F)O.O=C([C@@H](N)C(C)C)N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C([15NH][13C@H]([13C](O)=O)[13CH2][13CH2][13CH2][13CH2][15NH2])=O)CCC(N)=O)=O)CC(C)C)=O)CCC(N)=O)=O)CC(C)C)=O)=O)C)=O)=O)CCC(O)=O)=O)CO)=O)[C@@H](C)O.[x]

Molecular Weight

1238.31 (free acid)

References & Citations

[1]Bronsema KJ, et al. Absolute quantification of the total and antidrug antibody-bound concentrations of recombinant human α-glucosidase in human plasma using protein G extraction and LC-MS/MS. Anal Chem. 2015 Apr 21;87(8):4394-401.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P5201S1/VTSEGAGLQLQK-13C6-15N2-TFA-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P5201S1/

Clinical Information

No Development Reported

Curated Selection

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