VTSEGAGLQLQK-13C6,15N2 (TFA)
VTSEGAGLQLQK-13C6,15N2 (TFA) is the 13C- and 15N-labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA), which can be used to bind anti-drug antibodies in plasma and quantitatively analyze the therapeutic effect[1][2].
Product Specifications
UNSPSC
12352209
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/vtsegaglqlqk-13c6-15n2-tfa.html
Solubility
10 mM in DMSO
Smiles
O=C(C(F)(F)F)O.O=C([C@@H](N)C(C)C)N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C([15NH][13C@H]([13C](O)=O)[13CH2][13CH2][13CH2][13CH2][15NH2])=O)CCC(N)=O)=O)CC(C)C)=O)CCC(N)=O)=O)CC(C)C)=O)=O)C)=O)=O)CCC(O)=O)=O)CO)=O)[C@@H](C)O.[x]
Molecular Formula
C46 13C6H91N13 15N2O19.xC2HF3O2
Molecular Weight
1238.31 (free acid)
References & Citations
[1]Bronsema KJ, et al. Absolute quantification of the total and antidrug antibody-bound concentrations of recombinant human α-glucosidase in human plasma using protein G extraction and LC-MS/MS. Anal Chem. 2015 Apr 21;87 (8) :4394-401.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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