Bimatoprost acid

Bimatoprost acid (17-Phenyl trinor PGF2α), the acid hydrolysis product of Bimatoprost (HY-B0191), is a potent agonist of prostaglandin FP receptor[1].

Product Specifications

CAS Number

[38344-08-0]

Product Name Alternative

17-Phenyl trinor PGF2α

UNSPSC

12352005

Hazard Statement

H361

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/bimatoprost-acid.html

Solubility

10 mM in DMSO

Smiles

O=C(O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C[C@@H]1O

Molecular Formula

C23H32O5

Molecular Weight

388.50

Precautions

P280-P405-P501

References & Citations

[1]Ichhpujani P, et al. Comparison of human ocular distribution of bimatoprost and latanoprost. J Ocul Pharmacol Ther. 2012 Apr;28 (2) :134-45.|[2]Krauss AH, et al. Update on the mechanism of action of bimatoprost: a review and discussion of new evidence. Surv Ophthalmol. 2004 Mar;49 Suppl 1:S5-11.