PE-Labeled Human CD4 Protein, His Tag (Site-specific conjugation)
PE-Labeled Human CD4, His Tag (CD4-HP2E3) is produced via site-specific conjugation of PE to Human CD4, His Tag under optimal conditions with a proprietary technology. Human CD4, His Tag is expressed from human 293 cells (HEK293) . It contains AA Lys 26 - Pro 396 (Accession # P01730-1) .
Product Specifications
Background
T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 45.0 kDa.
Accession Number
P01730-1
Expression Region
Lys 26 - Pro 396
Host
HEK293
Target
CD4
Conjugation
PE Labeled
Tag
C-10xHis
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Format
Powder
Buffer
PBS, 0.5% BSA, pH7.4
Additives
Trehalose
Molecular Weight
45.0 kDa
Shipping Conditions
RT
Storage Conditions
-20°C, aviod light
Package Size
200tests*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CD4-HP2E3.pdf
Species
Human
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