5-chloro-2'-deoxyuridine (Highly Pure)

<strong>5-chloro-2'-deoxyuridine (Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2012300_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 262.6 g/mol_x000D_ <strong>Supplied as:</strong> Crystals_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> Chlorodeoxyuridine, CldU_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Brandon ML, Mi L, Chaung W, Teebor G, Boorstein RJ. 5-chloro-2'-deoxyuridine cytotoxicity results from base excision repair of uracil subsequent to thymidylate synthase inhibition Mutat Res. 2000 Mar 20;459(2):161-9._x000D_ 2: Yamada K, Semba R, Ding X, Ma N, Nagahama M. Discrimination of cell nuclei in early S-phase, mid-to-late S-phase, and G(2)/M-phase by sequential administration of 5-bromo-2'-deoxyuridine and 5-chloro-2'-deoxyuridine J Histochem Cytochem. 2005 Nov;53(11):1365-70._x000D_ 3: Hale JT, Bigelow JC, Mathews LA, McCormack JJ. Analytical and pharmacokinetic studies with 5-chloro-2'-deoxycytidine Biochem Pharmacol. 2002 Nov 15;64(10):1493-502._x000D_ 4: Hoheisel JD, Lehrach H. Quantitative measurements on the duplex stability of 2,6-diaminopurine and 5-chloro-uracil nucleotides using enzymatically synthesized oligomers FEBS Lett. 1990 Nov 12;274(1-2):103-6._x000D_ 5: Yennek S, Tajbakhsh S. DNA asymmetry and cell fate regulation in stem cells Semin Cell Dev Biol. 2013 Aug-Sep;24(8-9):627-42._x000D_ 6: Pivazyan AD, Birks EM, Wood TG, Lin TS, Prusoff WH. Inhibition of poly(ADP-ribose)polymerase activity by nucleoside analogs of thymidine Biochem Pharmacol. 1992 Sep 1;44(5):947-53._x000D_ 7: Smee DF, Humphreys DE, Hurst BL, Barnard DL. Antiviral activities and phosphorylation of 5-halo-2'-deoxyuridines and N-methanocarbathymidine in cells infected with vaccinia virus Antivir Chem Chemother. 2008;19(1):15-24._x000D_ 8: Liu W. Single Molecular Resolution to Monitor DNA Replication Fork Dynamics upon Stress by DNA Fiber Assay Bio Protoc. 2021 Dec 20;11(24):e4269._x000D_ 9: Eremeeva E, Abramov M, Marlière P, Herdewijn P. The 5-chlorouracil:7-deazaadenine base pair as an alternative to the dT:dA base pair Org Biomol Chem. 2016 Dec 20;15(1):168-176._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/22428623">10: Rivero CW, Britos CN, Lozano ME, Sinisterra JV, Trelles JA. Green biosynthesis of floxuridine by immobilized microorganisms FEMS Microbiol Lett. 2012 Jun;331(1):31-6. </a>_x000D_ _x000D_ <strong>Products Related to 5-chloro-2'-deoxyuridine (Highly Pure) can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>