Tanshinone IIB
Tanshinone IIB is a major active constituent of the roots of Salvia miltiorrhiza (Danshen) widely used for the research of stroke and coronary heart disease in Asian countries. Tanshinone IIB has a neuroprotective effect via inhibition of apoptosis[1].
Product Specifications
CAS Number
17397-93-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/tanshinone-iib.html
Purity
99.0
Solubility
Methanol : 0.5 mg/mL (ultrasonic; warming)
Smiles
O=C(C1=C2C=CC3=C1CCC[C@@]3(CO)C)C(C4=C2OC=C4C)=O
Molecular Formula
C19H18O4
Molecular Weight
310.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Xue-Qing Yu, et al. Tanshinone IIB, a primary active constituent from Salvia miltiorrhiza, exerts neuroprotective effect via inhibition of neuronal apoptosis in vitro. Phytother Res. 2008 Jun;22 (6) :846-50.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
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