Tanshinone IIB

Tanshinone IIB is a major active constituent of the roots of Salvia miltiorrhiza (Danshen) widely used for the research of stroke and coronary heart disease in Asian countries. Tanshinone IIB has a neuroprotective effect via inhibition of apoptosis[1].

Product Specifications

CAS Number

[17397-93-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/tanshinone-iib.html

Purity

99.0

Solubility

Methanol : 0.5 mg/mL (ultrasonic; warming)

Smiles

O=C(C1=C2C=CC3=C1CCC[C@@]3(CO)C)C(C4=C2OC=C4C)=O

Molecular Formula

C19H18O4

Molecular Weight

310.34

Precautions

H302, H315, H319, H335

References & Citations

[1]Xue-Qing Yu, et al. Tanshinone IIB, a primary active constituent from Salvia miltiorrhiza, exerts neuroprotective effect via inhibition of neuronal apoptosis in vitro. Phytother Res. 2008 Jun;22 (6) :846-50.