Coronatine

Coronatine is a plant growth regulator that mimicks the jasmonic acid-isoleucine conjugate (JA-Ile), targets the jasmonic acid receptor COI1, activates the jasmonic acid signaling pathway, thereby inhibiting salicylic acid (SA) -dependent defense responses. Coronatine antagonizes the stomatal closure, induces plant cell necrosis and chlorosis, interfers with plant hormone balance, thereby promoting pathogen infection[1][2][3][4].

Product Specifications

CAS Number

[62251-96-1]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Bacterial; Phytohormone

Type

Natural Products

Related Pathways

Anti-infection; Others

Applications

COVID-19-immunoregulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/coronatine.html

Purity

99.39

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=C[C@H](CC)C[C@@]2([H])[C@]1([H])CCC2=O)N[C@]3(C[C@@H]3CC)C(O)=O

Molecular Formula

C18H25NO4

Molecular Weight

319.40

Precautions

H302, H315, H319, H335

References & Citations

[1] Geng X, et al. The phytotoxin coronatine is a multifunctional component of the virulence armament of Pseudomonas syringae. Planta. 2014 Dec;240 (6) :1149-65.|[2]Weiler EW, et al. The Pseudomonas phytotoxin coronatine mimics octadecanoid signalling molecules of higher plants. FEBS Lett. 1994 May 23;345 (1) :9-13. |[3] Zheng XY, et al. Coronatine promotes Pseudomonas syringae virulence in plants by activating a signaling cascade that inhibits salicylic acid accumulation. Cell Host Microbe. 2012 Jun 14;11 (6) :587-96. |[4]Li ZH, et al. Application of coronin as a novel cotton defoliator. State Intellectual Property Office of the People's Republic of China. CN102239876A.