(R) -Monepantel

(R) -Monepantel (AAD2224) is the optical R-enantiomer of monepantel. (R) -Monepantel has no nematocidal effect, is inactive[1].

Product Specifications

CAS Number

[887148-70-1]

Product Name Alternative

(R) -AAD1566

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

NAChR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/r-monepantel.html

Purity

99.95

Solubility

10 mM in DMSO

Smiles

O=C(N[C@](C)(C#N)COC1=CC(C#N)=CC=C1C(F)(F)F)C2=CC=C(SC(F)(F)F)C=C2

Molecular Formula

C20H13F6N3O2S

Molecular Weight

473.39

Precautions

H302, H315, H319, H335

References & Citations

[1]Roland Baur, et al. Monepantel irreversibly binds to and opens Haemonchus contortus MPTL-1 and Caenorhabditis elegans ACR-20 receptors. Mol Pharmacol, 2015, 81, 7.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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