SU5205
SU5205 is an inhibitor of VEGFR2 (FLK-1), with an IC50 of 9.6 μM[1].
Product Specifications
CAS Number
3476-86-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/su5205.html
Purity
98.02
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C1NC2=C(C=CC=C2)/C1=C/C3=CC=C(F)C=C3
Molecular Formula
C15H10FNO
Molecular Weight
239.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Torsten K, et, al. Synthesis and radiopharmacological investigation of 3-[4'-[ (18) F]fluorobenzylidene]indolin-2-one as possible tyrosine kinase inhibitor. Bioorg Med Chem. 2009 Nov 15; 17 (22) : 7732-42.|[2]Huh S, et al. Melanogenesis inhibitory effect of fatty acid alkyl esters isolated from Oxalis triangularis. Biol Pharm Bull. 2010;33 (7) :1242-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
VEGFR2/KDR/Flk-1
Available Sizes
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