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DKK-1, Human (89a.a, HEK293, mFc)

DKK-1 Proteinas are potent antagonists of canonical Wnt signaling, inhibiting LRP5/6-Wnt interactions and forming a ternary complex with KREMEN to promote LRP5/6 internalization.In addition to its proapoptotic function by antagonizing KREMEN1 independently of Wnt, DKK-1 also exhibits antiapoptotic activity. DKK-1 Protein, Human (89a.a, HEK293, mFc) is the recombinant human-derived DKK1 protein, expressed by HEK293 , with C-mFc labeled tag.

Product Specifications

Product Name Alternative

DKK-1 Protein, Human (89a.a, HEK293, mFc), Human, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/dkk1-protein-human-89a-a-hek293-mfc.html

Molecular Formula

22943 (Gene_ID) O94907 (M178-H266) (Accession)

Molecular Weight

Approximately 45-53 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Scientific Category

Recombinant Proteins

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