Antibiofilm agent-13
Product Specifications
UNSPSC Description
Antibiofilm agent-13 (compound 14b) is a potent antibacterial agent that displays a broad-spectrum antimicrobial activity. Antibiofilm agent-13 could disintegrate the integrity of bacterial cell membranes by destroying transmembrane potential and enhancing membrane permeability, and causing the generation of intracellular ROS and the leakage of DNA and proteins, ultimately leading to bacterial death. Antibiofilm agent-13 inhibits both Gram-positive bacteria (MIC of 0.5-1 μg/mL) and Gram-negative bacteria (MIC of 1-32 μg/mL)[1].
Target Antigen
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibiofilm-agent-13.html
Smiles
O=C(C1=CC=C(OCCC[N+]2=CC=C(OCCCCCC)C=C2)C=C1)/C=C/C3=CC=C(OCCC[N+]4=CC=C(OCCCCCC)C=C4)C=C3.[Br-].[Br-]
Molecular Weight
840.72
References & Citations
[1]Siyu Yang, et al. Development of membrane-targeting chalcone derivatives as antibacterial agents against multidrug-resistant bacteria. Eur J Med Chem. 2024 Oct 18:280:116969.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168258/Antibiofilm-agent-13-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168258/
Clinical Information
No Development Reported
CAS Number
9007-83-4
Curated Selection
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