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Trilaciclib (hydrochloride) (Standard)

Trilaciclib (hydrochloride) (Standard) is the analytical standard of Trilaciclib (hydrochloride) . This product is intended for research and analytical applications. Trilaciclib hydrochloride (G1T28 hydrochloride) is a CDK4/6 inhibitor with IC50s of 1 nM and 4 nM for CDK4 and CDK6, respectively[1].

Product Specifications

CAS Number

1977495-97-8

Product Name Alternative

G1T28 (hydrochloride) (Standard)

UNSPSC

12352005

Target

CDK; Reference Standards

Type

Reference Standards

Related Pathways

Cell Cycle/DNA Damage; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/trilaciclib-hydrochloride-standard.html

Smiles

O=C1C2=CC3=CN=C(NC4=CC=C(N5CCN(C)CC5)C=N4)N=C3N2C6(CCCCC6)CN1.[H]Cl.[H]Cl

Molecular Formula

C24H32Cl2N8O

Molecular Weight

519.47

References & Citations

[1]Bisi JE, et al. Preclinical Characterization of G1T28: A Novel CDK4/6 Inhibitor for Reduction of Chemotherapy-Induced Myelosuppression. Mol Cancer Ther. 2016 May;15 (5) :783-93.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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