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2A3

2A3 is a highly efficient and precise SHAPE reagent with powerful biomembrane penetration capabilities, suitable for both in vivo and in vitro RNA structure detection. 2A3 can not only effectively probe most RNA loops but also better capture local nucleotide dynamics, thus enabling it to readily detect regions of ribonucleoprotein complexes that are typically inaccessible to other compounds[1].

Product Specifications

CAS Number

2765091-45-8

UNSPSC

12352005

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/2a3.html

Purity

97.0

Solubility

DMSO : 20 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=CC=CN=C1N)N2C=NC=C2

Molecular Formula

C9H8N4O

Molecular Weight

188.19

References & Citations

[1]Marinus T, et al. A novel SHAPE reagent enables the analysis of RNA structure in living cells with unprecedented accuracy[J]. Nucleic acids research, 2021, 49 (6) : e34-e34.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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CCL3 (C C Motif Chemokine 3, CCL 3, CCL3_HUMAN, Chemokine C C Motif Ligand 3, Chemokine CC Motif Ligand 3, G0/G1 Switch Regulatory Protein 19 1, G0/G1 Switch Regulatory Protein 19-1, G0S19 1, G0S19 1 Protein, Heparin Binding Chemotaxis Protein, L2G25B, LD78 alpha, LD78-alpha (4-69), LD78ALPHA, Macrophage Inflammatory Protein 1 alpha, Macrophage Inflammatory Protein 1-alpha, MIP 1 alpha, MIP 1A, MIP-1-alpha, MIP-1-alpha (4-69), MIP1A, PAT 464.1, SCYA 3, SCYA3, SIS alpha, SIS beta, SIS-beta, Small Inducible Cytokine A3, Small-inducible Cytokine A3, Tonsillar Lymphocyte LD78 alpha Protein) (PE) discontinued
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