Antibacterial agent 247
Antibacterial agent 247 (compund 30b) is a bacterial antagonist that significantly inhibits the formation of Pseudomonas aeruginosa biofilm (IC50=5.8 μM) and multiple virulence phenotypes, and enhances its interaction with Tob Antibacterial activity of combined therapy with ampicillin and polymyxin B[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-247.html
Smiles
O=C1C(O)=C(N(C(C)=C1)C)C(NCCCCCCCCCNC2=CC=NC3=C2C=CC(Cl)=C3)=O
Molecular Formula
C26H33ClN4O3
Molecular Weight
485.02
References & Citations
[1]Miao ZY, et al. Hybrids of 3-Hydroxypyridin-4 (1H) -ones and Long-Chain 4-Aminoquinolines as Potent Biofilm Inhibitors of Pseudomonas aeruginosa Potentiate Tobramycin and Polymyxin B Activity. J Med Chem. 2024 Sep 26;67 (18) :16835-16857.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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