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HOXB7 8–25

HOXB7 8–25 (MDM2 32-46) is an MDM2-derived peptide epitope and can elicit antigen-specifc and tumor-reactive CD4+ T cell responses[1].

Product Specifications

Product Name Alternative

MDM2 32-46

UNSPSC

12352209

Target

Ligands for E3 Ligase

Type

Peptides

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hoxb7-8-25.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H](C(C)C)C(NCC(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]1NCCC1

Molecular Formula

C75H135N19O20

Molecular Weight

1622.99

References & Citations

[1]Kono M, et al. Interruption of MDM2 signaling augments MDM2-targeted T cell-based antitumor immunotherapy through antigen-presenting machinery. Cancer Immunol Immunother. 2021;70 (12) :3421-3434.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Isoform

MDM2

Frequently Asked Questions

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