AKT3 (PKB Gamma) Antibody

<strong>AKT3 (PKB Gamma) Antibody</strong>_x000D_ <strong>Catalog number:</strong> B2015777_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 ¬∞C_x000D_ <strong>Keywords:</strong> protein kinase B gamma (PKB gamma)_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Tschopp O, Yang ZZ, Brodbeck D, Dummler BA, Hemmings-Mieszczak M, Watanabe T, Michaelis T, Frahm J, Hemmings BA. Essential role of protein kinase B gamma (PKB gamma/Akt3) in postnatal brain development but not in glucose homeostasis Development. 2005 Jul;132(13):2943-54._x000D_ 2: Hers I, Vincent EE, Tavar√© JM. Akt signalling in health and disease Cell Signal. 2011 Oct;23(10):1515-27._x000D_ 3: Iida M, Harari PM, Wheeler DL, Toulany M. Targeting AKT/PKB to improve treatment outcomes for solid tumors Mutat Res. 2020 Jan-Apr;819-820:111690._x000D_ 4: Bauer B, Baier G. Protein kinase C and AKT/protein kinase B in CD4+ T-lymphocytes: new partners in TCR/CD28 signal integration Mol Immunol. 2002 Jun;38(15):1087-99._x000D_ 5: Corum DG, Jenkins DP, Heslop JA, Tallent LM, Beeson GC, Barth JL, Schnellmann RG, Muise-Helmericks RC. PDE5 inhibition rescues mitochondrial dysfunction and angiogenic responses induced by Akt3 inhibition by promotion of PRC expression J Biol Chem. 2020 Dec 25;295(52):18091-18104._x000D_ 6: Romano G. The role of the dysfunctional akt-related pathway in cancer: establishment and maintenance of a malignant cell phenotype, resistance to therapy, and future strategies for drug development Scientifica (Cairo). 2013;2013:317186._x000D_ 7: Nakatani K, Sakaue H, Thompson DA, Weigel RJ, Roth RA. Identification of a human Akt3 (protein kinase B gamma) which contains the regulatory serine phosphorylation site Biochem Biophys Res Commun. 1999 Apr 21;257(3):906-10._x000D_ 8: Brodbeck D, Hill MM, Hemmings BA. Two splice variants of protein kinase B gamma have different regulatory capacity depending on the presence or absence of the regulatory phosphorylation site serine 472 in the carboxyl-terminal hydrophobic domain J Biol Chem. 2001 Aug 3;276(31):29550-8._x000D_ 9: Levenga J, Wong H, Milstead R, LaPlante L, Hoeffer CA. Immunohistological Examination of AKT Isoforms in the Brain: Cell-Type Specificity That May Underlie AKT's Role in Complex Brain Disorders and Neurological Disease Cereb Cortex Commun. 2021 May 28;2(2):tgab036._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/9516411">10: Calera MR, Martinez C, Liu H, Jack AK, Birnbaum MJ, Pilch PF. Insulin increases the association of Akt-2 with Glut4-containing vesicles J Biol Chem. 1998 Mar 27;273(13):7201-4. </a>_x000D_ _x000D_ <strong>Products Related to AKT3 (PKB Gamma) Antibody can be found at</strong> <a href="https://moleculardepot.com/product-category/Antibodies/"> Antibodies</a>