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6- (L-1,2,3-Trihydroxybutyl) -pterin

6- (L-1,2,3-Trihydroxybutyl) -pterin is a derivative of L-biopterin and is the oxidized form of tetrahydro-L-biopterin (BH4) as well as D-biopterin. Co-ingestion of 6- (L-1,2,3-Trihydroxybutyl) -pterin (0.5%) with the carcinogen 4-dimethylaminoazobenzene reduces the incidence of 4-dimethylaminoazobenzene-induced liver tumors in rats. 6- (L-1,2,3-Trihydroxybutyl) -pterin has been used as an internal standard for the LC-MS quantification of biopterin and neopterin in rat plasma.

Product Specifications

CAS Number

13392-24-0

UNSPSC

12352005

Target

Drug Derivative

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/6-l-1-2-3-trihydroxybutyl-pterin.html

Smiles

C[C@H](O)[C@H](O)[C@@H](O)C1=NC(C(N=C(N)N2)=O)=C2N=C1

Molecular Formula

C10H13N5O4

Molecular Weight

267.24

References & Citations

[1]Sasaki, et al. Effect of polyhydroxy-alkylpterins on the development of liver cancers in the rat fed with 4-dimethylaminoazobenzene. Gan. 55, 297-304 (1964) .

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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