Harmol (Standard)

Harmol (Standard) is the analytical standard of Harmol (HY-107811) . This product is intended for research and analytical applications. Harmol hydrochloride is an orally active β-carboline alkaloid. Harmol hydrochloride is a TFEB activator and monoamine oxidase inhibitor. Harmol can induce cell mitosis, Autophagy and Apoptosis. Harmol promotes the degradation of α-synuclein by regulating the autophagy-lysosomal pathway. Harmol has anti-tumor, anti-depressant and anti-aging activities. Harmol improves motor impairment in a mouse Parkinson's disease model[1][2][3][4].

Product Specifications

CAS Number

[487-03-6]

UNSPSC

12352005

Target

Apoptosis; Autophagy; Mitosis; Monoamine Oxidase; Reference Standards; α-synuclein

Type

Reference Standards

Related Pathways

Apoptosis; Autophagy; Neuronal Signaling; Others

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/harmol-standard.html

Smiles

OC1=CC2=C(C=C1)C3=C(C(C)=NC=C3)N2

Molecular Formula

C12H10N2O

Molecular Weight

198.22

References & Citations

[1]Blei F, et al. Simultaneous Production of Psilocybin and a Cocktail of β-Carboline Monoamine Oxidase Inhibitors in "Magic" Mushrooms. Chemistry. 2020 Jan 13;26 (3) :729-734.