Brocresine
Brocresine (NSD-1065) is an orally active histidine decarboxylase inhibitor and inhibits the formation of histamine from histidine. Brocresine is also a L-amino acid decarboxylase inhibitor with both a peripheral and central action. Brocresine inhibits gastric secretory response to administration of exogenous gastrin[1][2].
Product Specifications
CAS Number
555-65-7
Product Name Alternative
NSD-1065
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/brocresine.html
Smiles
OC1=CC(CON)=CC=C1Br
Molecular Formula
C7H8BrNO2
Molecular Weight
218.05
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Howse PM, et al. Brocresine in Parkinson's disease. Action of a peripheral and central decarboxylase inhibitor in potentiating levodopa. J Neurol Neurosurg Psychiatry. 1973 Feb;36 (1) :27-9. |[2]Fletcher TL, et al. Effect of 4-bromo-3-hydroxybenzyloxyamine (Brocresine) on gastric secretion in pouch dogs. Proc Soc Exp Biol Med. 1969 Oct;132 (1) :205-11.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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