TH-Z145
TH-Z145, a lipophilic bisphosphonate, is a FPPS inhibitor (IC50: 210 nM) [1].
Product Specifications
CAS Number
[2260887-57-6]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/th-z145.html
Concentration
10mM
Purity
99.69
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=P(O)(C(P(O)(O)=O)CC1=CC(OCCCCCCCC)=CC=C1)O
Molecular Formula
C16H28O7P2
Molecular Weight
394.34
References & Citations
[1]Xia Y, et al. The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery. Cell. 2018 Nov 1;175 (4) :1059-1073.e21.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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