M-PEG6-Amine
M-PEG6-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG6-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[184357-46-8]
UNSPSC
12352203
Hazard Statement
H314
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/m-peg6-amine.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
COCCOCCOCCOCCOCCOCCN
Molecular Formula
C13H29NO6
Molecular Weight
295.37
Precautions
H314
References & Citations
[1]Hervé Bouchard, et al. Peptidic linkers and cryptophycin conjugates, useful in therapy, and their preparation. WO2018206635A1.|[2]Austin G Wardrip, et al. Length-Independent Charge Transport in Chimeric Molecular Wires. Angew Chem Int Ed Engl. 2016 Nov 7;55 (46) :14267-14271.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; PEG Linkers
Available Sizes
Curated Selection
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