M-PEG6-Amine

M-PEG6-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG6-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Product Specifications

CAS Number

[184357-46-8]

UNSPSC

12352203

Hazard Statement

H314

Target

ADC Linker; PROTAC Linkers

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/m-peg6-amine.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

COCCOCCOCCOCCOCCOCCN

Molecular Formula

C13H29NO6

Molecular Weight

295.37

Precautions

H314

References & Citations

[1]Hervé Bouchard, et al. Peptidic linkers and cryptophycin conjugates, useful in therapy, and their preparation. WO2018206635A1.|[2]Austin G Wardrip, et al. Length-Independent Charge Transport in Chimeric Molecular Wires. Angew Chem Int Ed Engl. 2016 Nov 7;55 (46) :14267-14271.