ML-109
ML-109 is a potent and full thyroid stimulating hormone receptor (TSHR) agonist, with an EC50 of 40 nM.
Product Specifications
CAS Number
1186649-91-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
TSH Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/ML-109.html
Purity
99.02
Solubility
DMSO : 83.33 mg/mL (ultrasonic)
Smiles
CC(NC1=CC=C(OCC2=CC(C(N3CC4=CC=CC=C4)NC5=C(C(O)=CC=C5)C3=O)=CC=C2OC)C=C1)=O
Molecular Formula
C31H29N3O5
Molecular Weight
523.58
Precautions
H302, H315, H319, H335
References & Citations
[1]Neumann S, et al. Small-molecule agonists for the thyrotropin receptor stimulate thyroid function in human thyrocytes and mice. Proc Natl Acad Sci U S A. 2009 Jul 28;106 (30) :12471-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
HA710035 100 µg
Alpaca IgG2b (Fcγ Fragment specific), AlpHcAbs® Rabbit antibody (Biotin)
Sign In for Pricing
View Details 
KN417134 1 Kit
beta 1 Adrenergic Receptor (ADRB1) Human Gene Knockout Kit (CRISPR)
Sign In for Pricing
View Details 
BNC680833-500 1x 500 µL
Calponin-1 (CALP + CNN1/832), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNUB2881-100 1x 100 µL
CD63 (Late Endosomes Marker) (LAMP3/2881), 0.2mg/mL
Sign In for Pricing
View Details