Anisomycin
Anisomycin is a potent protein synthesis inhibitor which interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system[1]. Anisomycin is a JNK activator, which increases phospho-JNK[2][3]. Anisomycin is a bacterial antibiotic[4].
Product Specifications
CAS Number
22862-76-6
Product Name Alternative
Flagecidin; Wuningmeisu C
UNSPSC
12352005
Hazard Statement
H301
Target
Antibiotic; Apoptosis; Bacterial; DNA/RNA Synthesis; JNK; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Cell Cycle/DNA Damage; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/Anisomycin.html
Concentration
10mM
Purity
99.82
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 4 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O[C@@H]1[C@@H](OC(C)=O)[C@@H](CC2=CC=C(OC)C=C2)NC1
Molecular Formula
C14H19NO4
Molecular Weight
265.31
Precautions
H301
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
JNK
Available Sizes
Frequently Asked Questions
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