Guanosine-15N5

Guanosine-15N5 is the 15N labeled Guanosine[1]. Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity[2].

Product Specifications

Product Name Alternative

DL-Guanosine-15N5; Vernine-15N5

UNSPSC

12352005

Hazard Statement

H301

Target

Endogenous Metabolite; HSV

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/guanosine-15n5.html

Purity

99.60

Solubility

H2O : 1 mg/mL (ultrasonic; warming)

Smiles

O[C@H]1[C@@H](O)[C@H]([15N]2C([15N]=C([15NH2])[15NH]C3=O)=C3[15N]=C2)O[C@@H]1CO

Molecular Formula

C10H13 15N5O5

Molecular Weight

288.21

Precautions

H301

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]De Clercq E1. Guanosine analogues as anti-herpesvirus agents. Nucleosides Nucleotides Nucleic Acids. 2000 Oct-Dec;19 (10-12) :1531-41.