Rifapentine (Standard)

Rifapentine (Standard) is the analytical standard of Rifapentine. This product is intended for research and analytical applications. Rifapentine (DL 473) is an antibiotic used in tuberculosis research[1].

Product Specifications

CAS Number

[61379-65-5]

Product Name Alternative

DL 473 (Standard) ; Cyclopentylrifampicin (Standard)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Bacterial; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/rifapentine-standard.html

Purity

87.98

Smiles

OC(C1=C(C2=O)C(O[C@@]2(O/C=C/[C@@H]([C@H]([C@@]([C@@H]3C)([H])OC(C)=O)C)OC)C)=C(C)C(O)=C1C(O)=C4NC(/C(C)=C\C=C\[C@@H]([C@@H]([C@@H](C)[C@H]3O)O)C)=O)=C4/C=N/N5CCN(C6CCCC6)CC5

Molecular Formula

C47H64N4O12

Molecular Weight

877.03

Precautions

H302, H315, H319, H335

References & Citations

[1]Sharma, S.K., et al., Rifamycins (rifampicin, rifabutin and rifapentine) compared to isoniazid for preventing tuberculosis in HIV-negative people at risk of active TB. Cochrane Database Syst Rev, 2013. 7: p. CD007545.|[2]Klemens SP, et al. Activity of rifapentine against Mycobacterium avium infection in beige mice. J Antimicrob Chemother. 1992 May;29 (5) :555-61.|[3] Albano M, et al. In Vitro Activity of Rifampin, Rifabutin, Rifapentine, and Rifaximin against Planktonic and Biofilm States of Staphylococci Isolated from Periprosthetic Joint Infection. Antimicrob Agents Chemother. 2019 Oct 22;63 (11) :e00959-19.|[4]Rifat D, et al. Pharmacokinetics of rifapentine and rifampin in a rabbit model of tuberculosis and correlation with clinical trial data. Sci Transl Med. 2018 Apr 4;10 (435) :eaai7786.