Lp-PLA2-IN-17
Lp-PLA2-IN-17 (Compound 39) is an inhibitor of Lp-PLA2. Lp-PLA2-IN-17 can be used to study disorders involving the hydrolysis of oxidized lipids into two inflammatory substances with the participation of Lp-PLA2[1].
Product Specifications
CAS Number
1818842-74-8
UNSPSC
12352005
Target
Phospholipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/lp-pla2-in-17.html
Solubility
10 mM in DMSO
Smiles
FC(F)(C1=CC(OC2=CC=C(COC3=NC4=NC=C(N4C=C3)C5=CN=CN=C5)C=C2Cl)=CC=C1Cl)F
Molecular Formula
C24H14Cl2F3N5O2
Molecular Weight
532.30
References & Citations
[1]Shen Jianhua, et al. Bicyclic compound used as an lp-pla2 inhibitor, and preparation method and pharmaceutical use thereof. U.S., 2016-11-17.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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