Isorhamnetin 3-gentiobioside

Isorhamnetin 3-gentiobioside is a flavonoid with activity of promoting cancer cell proliferation. Isorhamnetin 3-gentiobioside is an activator of DNA synthesis in MCF-7 human breast cancer cells with an EC50 of 3.1 μg/mL. Isorhamnetin 3-gentiobioside exhibits ABTS radical scavenging activity with an IC50 of 33.43 μg/mL. The compound can be used to study the bidirectional regulatory mechanism of cancer[1][2].

Product Specifications

CAS Number

[17429-69-5]

UNSPSC

12352005

Hazard Statement

H302, H315

Target

DNA/RNA Synthesis

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/isorhamnetin-3-gentiobioside.html

Purity

99.69

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

OC1=CC=C(C(OC2=C3C(O)=CC(O)=C2)=C(O[C@@H]4O[C@H](CO[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)C3=O)C=C1OC

Molecular Formula

C28H32O17

Molecular Weight

640.54

Precautions

H302, H315

References & Citations

[1]Yang C , Yang Y , Akber A H , et al. Bioassay-guided isolation of antioxidants from Astragalus altaicus by combination of chromatographic techniques[J]. Journal of Separation ence, 2015, 35 (8) :977-983.|[2]Ninfali P, et al. Characterization and biological activity of the main flavonoids from Swiss Chard (Beta vulgaris subspecies cycla) . Phytomedicine. 2007 Feb;14 (2-3) :216-21.