APC-Labeled Human CLEC12A / MICL / CLL-1 Protein, His Tag (Site-specific conjugation)
APC-Labeled Human CLEC12A, His Tag (CLA-HA248) is produced via conjugation of APC to Human CLEC12A, His Tag with a new generation site-specific technology under optimal conditions with a proprietary technology. Human CLEC12A, His Tag is expressed from human 293 cells (HEK293) . It contains AA His 65 - Ala 265 (Accession # NP_612210.4) .
Product Specifications
Background
CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.
Specifications
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 27.3 kDa.
Expression Region
His 65 - Ala 265
Host
HEK293
Target
CLEC12A
Conjugation
APC Labeled
Tag
N-10xHis
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Format
Powder
Buffer
PBS, 0.5% BSA, pH7.4
Additives
Trehalose
Molecular Weight
27.3 kDa
Shipping Conditions
RT
Storage Conditions
-20°C, aviod light
Package Size
200tests*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CLA-HA248.pdf
Species
Human
Curated Selection
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