Fmoc-leucine-13C6,15N
Product Specifications
UNSPSC Description
Fmoc-leucine-13C6,15N is a 15N-labeled and 13C-labled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity
Target Antigen
Isotope-Labeled Compounds; PPAR
Type
Isotope-Labeled Compounds
Related Pathways
Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Others;Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/fmoc-leucine-13c6-15n.html
Solubility
10 mM in DMSO
Smiles
[13CH3][13CH]([13CH3])[13CH2][13C@@H]([13C](O)=O)[15NH]C(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O
Molecular Weight
360.36
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-248.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-248.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-101064S1/Fmoc-leucine-13C6-15N-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-101064S1/
Clinical Information
No Development Reported
CAS Number
1163133-36-5
Available Sizes
Curated Selection
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