Cryptotanshinone (Standard)

Cryptotanshinone (Standard) is the analytical standard of Cryptotanshinone. This product is intended for research and analytical applications. Cryptotanshinone is a natural compound extracted from the root of Salvia miltiorrhiza Bunge that shows antitumor activities. Cryptotanshinone inhibits STAT3 with an IC50 of 4.6 μM.

Product Specifications

CAS Number

[35825-57-1]

Product Name Alternative

Cryptotanshinon (Standard) ; Tanshinone c (Standard)

UNSPSC

12352005

Target

Autophagy; Reference Standards; STAT

Type

Reference Standards

Related Pathways

Autophagy; JAK/STAT Signaling; Others; Stem Cell/Wnt

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cryptotanshinone-standard.html

Smiles

O=C(C1=C2C=CC3=C1CCCC3(C)C)C(C4=C2OC[C@@H]4C)=O

Molecular Formula

C19H20O3

Molecular Weight

296.36

References & Citations

[1]Shin DS, et al. Cryptotanshinone inhibits constitutive signal transducer and activator of transcription 3 function through blocking the dimerization in DU145 prostate cancer cells. Cancer Res. 2009 Jan 1;69 (1) :193-202.|[2]Huang Y, et al. Cryptotanshinone reverses ovarian insulin resistance in mice through activation of insulin signaling and the regulation of glucose transporters and hormone synthesizing enzymes. Fertil Steril. 2014 Aug;102 (2) :589-596.e4.|[3]Ge Y, et al. Cryptotanshinone acts synergistically with imatinib to induce apoptosis of human chronic myeloid leukemia cells. Leuk Lymphoma. 2014 Jun 25:1-9.|[4]Kim EJ, et al. Antidiabetes and antiobesity effect of cryptotanshinone via activation of AMP-activated protein kinase. Mol Pharmacol. 2007 Jul;72 (1) :62-72. Epub 2007 Apr 11.