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(S) -Sitagliptin (phosphate) (Standard)

(S) -Sitagliptin (phosphate) (Standard) is the analytical standard of (S) -Sitagliptin (phosphate) . This product is intended for research and analytical applications. (S) -Sitagliptin phosphate is the less active S-enantiomer of Sitagliptin phosphate. Sitagliptin phosphate (MK-0431 phosphate) is a potent inhibitor of DPP4 with an IC50 of 19 nM in Caco-2 cell extracts[1].

Product Specifications

CAS Number

823817-58-9

Product Name Alternative

(S) -MK-0431 (phosphate) (Standard)

UNSPSC

12352005

Target

Autophagy; Dipeptidyl Peptidase; Reference Standards

Type

Reference Standards

Related Pathways

Autophagy; Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/s-sitagliptin-phosphate-standard.html

Smiles

O=C(N1CC2=NN=C(C(F)(F)F)N2CC1)C[C@@H](N)CC3=CC(F)=C(F)C=C3F.O=P(O)(O)O

Molecular Formula

C16H18F6N5O5P

Molecular Weight

505.31

References & Citations

[1]Chi-Hung Ho, et al. Biocatalytic Continuous Manufacturing of Diabetes Drug: Plantwide Process Modeling, Optimization, and Environmental and Economic Analysis. ACS Sustainable Chem. Eng. 2019, 7, 1, 1038-1051.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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