BE-10988
BE-10988 is a DNA topoisomerase inhibitor. BE-10988 inhibits the growth of Doxorubicin -resistant and vincristine-resistant P388 mouse leukemia cell lines by increasing the formation of DNA topoisomerase complexes[1].
Product Specifications
CAS Number
135261-89-1
UNSPSC
12352005
Target
Topoisomerase
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/be-10988.html
Smiles
O=C(C1=CSC(C2=CN(C)C(C(C=C3N)=O)=C2C3=O)=N1)N
Molecular Formula
C13H10N4O3S
Molecular Weight
302.31
References & Citations
[1]Oka H, et al. A NEW TOPOISOMERASE-II INHIBITOR, BE-10988, PRODUCED BY A STREPTOMYCETE I. TAXONOMY, FERMENTATION, ISOLATION AND CHARACTERIZATION[J]. The Journal of Antibiotics, 1991, 44 (5) : 486-491.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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