β-D-Glucan

β-D-glucan is a natural non-digestible polysaccharide and high biocompatibility that can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors as well as being easily internalized by murine or human macrophages, which is likely to attribute to a target delivery[1]. β-d-glucan is an enteric delivery vehicle for probiotics[2].

Product Specifications

CAS Number

[9041-22-9]

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Toll-like Receptor (TLR)

Type

Biochemical Assay Reagents

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/β-d-glucan.html

Purity

99.00

Solubility

1M NaOH : 50 mg/mL (ultrasonic; adjust pH to 12 with NaOH)

Smiles

[beta-D-Glucan]

Precautions

H302, H315, H319, H335

References & Citations

[1]Su Y, et al. pH-sensitive PEG-coated hyper-branched β-d-glucan derivative as carrier for CpG oligodeoxynucleotide delivery. Carbohydr Polym. 2020;246:116621. |[2]Gani A, et al. β-d-glucan as an enteric delivery vehicle for probiotics. Int J Biol Macromol. 2018;106:864-869. |[3]Jafaar ZM, et al. β-D-glucan inhibits endocrine-resistant breast cancer cell proliferation and alters gene expression. Int J Oncol. 2014;44 (4) :1365-1375.