Bacteria-Derived Ecotin Serine Protease Inhibitor

<strong>Bacteria-Derived Ecotin Serine Protease Inhibitor </strong>_x000D_ <strong>Catalog number:</strong> B2017152_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 500 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80C_x000D_ <strong>Keywords:</strong> Bacteria-Derived Ecotin Serine Protease Inhibitor_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: De Meyer F, Carlier A. Ecotin: A versatile protease inhibitor of bacteria and eukaryotes Front Microbiol. 2023 Jan 24;14:1114690._x000D_ 2: Ireland PM, Marshall L, Norville I, Sarkar-Tyson M. The serine protease inhibitor Ecotin is required for full virulence of Burkholderia pseudomallei Microb Pathog. 2014 Feb-Mar;67-68:55-8._x000D_ 3: Yang SQ, Wang CI, Gillmor SA, Fletterick RJ, Craik CS. Ecotin: a serine protease inhibitor with two distinct and interacting binding sites J Mol Biol. 1998 Jun 19;279(4):945-57._x000D_ 4: Garcia FB, Cabral AD, Fuhlendorf MM, da Cruz GF, Dos Santos JV, Ferreira GC, de Rezende BRC, Santana CM, Puzer L, Sasaki SD, Garcia W, Sperança MA. Functional and structural characterization of an ecotin-like serine protease inhibitor from Trypanosoma cruzi Int J Biol Macromol. 2020 May 15;151:459-466._x000D_ 5: Nagy ZA, Héja D, Bencze D, Kiss B, Boros E, Szakács D, Fodor K, Wilmanns M, Kocsis A, Dobó J, Gál P, Harmat V, Pál G. Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation J Biol Chem. 2022 Jun;298(6):101985._x000D_ 6: Nagy ZA, Szakács D, Boros E, Héja D, Vígh E, Sándor N, Józsi M, Oroszlán G, Dobó J, Gál P, Pál G. Ecotin, a microbial inhibitor of serine proteases, blocks multiple complement dependent and independent microbicidal activities of human serum PLoS Pathog. 2019 Dec 20;15(12):e1008232._x000D_ 7: McGrath ME, Gillmor SA, Fletterick RJ. Ecotin: lessons on survival in a protease-filled world Protein Sci. 1995 Feb;4(2):141-8._x000D_ 8: Clark EA, Walker N, Ford DC, Cooper IA, Oyston PC, Acharya KR. Molecular recognition of chymotrypsin by the serine protease inhibitor ecotin from Yersinia pestis J Biol Chem. 2011 Jul 8;286(27):24015-22._x000D_ 9: Eggers CT, Murray IA, Delmar VA, Day AG, Craik CS. The periplasmic serine protease inhibitor ecotin protects bacteria against neutrophil elastase Biochem J. 2004 Apr 1;379(Pt 1):107-18._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/10843853">10: Gillmor SA, Takeuchi T, Yang SQ, Craik CS, Fletterick RJ. Compromise and accommodation in ecotin, a dimeric macromolecular inhibitor of serine proteases J Mol Biol. 2000 Jun 16;299(4):993-1003. </a>_x000D_ _x000D_ <strong>Products Related to Bacteria-Derived Ecotin Serine Protease Inhibitor can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>