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PROTAC SMARCA2 degrader-3

PROTAC SMARCA2 degrader-3 is a PROTAC degrader of the SWI/SNF ATPase subunits, SMARCA2. PROTAC SMARCA2 degrader-3 has anticancer effects (WO2023244764A1; Compound 153) [1].

Product Specifications

CAS Number

3024266-69-8

UNSPSC

12352005

Target

Epigenetic Reader Domain; PROTACs

Type

Reference compound

Related Pathways

Epigenetics; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/protac-smarca2-degrader-3.html

Solubility

10 mM in DMSO

Smiles

NC1=C(C=C(C2=CC=CC=C2O)N=N1)C(C=N3)=CN3C(CC4)CCN4[C@@H](CC5)CC[C@@H]5C6=C(OCCN7C8C(NC(CC8)=O)=O)C7=CC=C6

Molecular Formula

C37H42N8O4

Molecular Weight

662.78

References & Citations

[1]Christopher G., et al. Compounds for the targeted degradation of smarca2. WO2023244764A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Frequently Asked Questions

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