PROTAC SMARCA2 degrader-3
PROTAC SMARCA2 degrader-3 is a PROTAC degrader of the SWI/SNF ATPase subunits, SMARCA2. PROTAC SMARCA2 degrader-3 has anticancer effects (WO2023244764A1; Compound 153) [1].
Product Specifications
CAS Number
3024266-69-8
UNSPSC
12352005
Target
Epigenetic Reader Domain; PROTACs
Type
Reference compound
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-smarca2-degrader-3.html
Solubility
10 mM in DMSO
Smiles
NC1=C(C=C(C2=CC=CC=C2O)N=N1)C(C=N3)=CN3C(CC4)CCN4[C@@H](CC5)CC[C@@H]5C6=C(OCCN7C8C(NC(CC8)=O)=O)C7=CC=C6
Molecular Formula
C37H42N8O4
Molecular Weight
662.78
References & Citations
[1]Christopher G., et al. Compounds for the targeted degradation of smarca2. WO2023244764A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
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