Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

DOTA-EB-TATE

DOTA-EB-TATE is composed of SST peptide derivative, DOTA-octreotate conjugated a common to an Evans blue analog (EB) . DOTA-EB-TATE is a peptide drug conjugate (PDC) improves the pharmacokinetics of SSTR2 analogs and reduces PRRT toxicity. DOTA-EB-TATE can also be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) [1][2].

Product Specifications

CAS Number

2151063-66-8

UNSPSC

12352209

Target

Peptide-Drug Conjugates (PDCs) ; Radionuclide-Drug Conjugates (RDCs) ; Somatostatin Receptor

Type

Peptides

Related Pathways

Antibody-drug Conjugate/ADC Related; GPCR/G Protein; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dota-eb-tate.html

Purity

95.42

Solubility

DMSO : 2 mg/mL (ultrasonic)

Smiles

O=[S](O)(C(C(C=C1)=C2C(O)=C1/N=N/C(C=CC(C(C=C3)=CC(C)=C3NC([C@H](CCCCNC(CCN(C(C4)=O)C(C4SCCC(N[C@@H](C(N[C@@H](CSSC[C@H](NC([C@](NC5=O)([H])[C@H](O)C)=O)C(N[C@H](C(O)=O)[C@H](O)C)=O)C(N[C@H](C(N[C@@H](C(N[C@H]5CCCCN)=O)CC6=CNC7=CC=CC=C67)=O)CC8=CC=CC=C8)=O)=O)CC9=CC=CC=C9)=O)=O)=O)NC(CN(CCN(CC%10)CC(O)=O)CCN(CCN%10CC(O)=O)CC(O)=O)=O)=O)=C%11)=C%11C)=CC([S](=O)(O)=O)=C2N)=O

Molecular Formula

C105H133N21O30S5

Molecular Weight

2329.63

References & Citations

[1]Rui Tian, et al. Evans Blue Attachment Enhances Somatostatin Receptor Subtype-2 Imaging and Radiotherapy. Theranostics. 2018 Jan 1;8 (3) :735-745. |[2]Vallabhajosula S. Design of Radiolabeled Peptide Radiopharmaceuticals[M]//Molecular Imaging and Targeted Therapy: Radiopharmaceuticals and Clinical Applications. Cham: Springer International Publishing, 2023: 577-607.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Frozen Tissue Sections, Cervix
CS503909 5x 5 µm

Frozen Tissue Sections, Cervix

Sign In for Pricing
View Details
Anln Mouse Gene Knockout Kit (CRISPR)
KN501312 1 Kit

Anln Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
OR14J1 (C-term) Rabbit Polyclonal Antibody
AP53020PU-N 400 µL

OR14J1 (C-term) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Tissue FFPE Sections, Ovary
CS802900 5x 5 µm

Tissue FFPE Sections, Ovary

Sign In for Pricing
View Details
Acyloxyacyl Hydrolase (AOAH) (NM_001177507) Human Over-expression Lysate
LC433253 20 µg

Acyloxyacyl Hydrolase (AOAH) (NM_001177507) Human Over-expression Lysate

Sign In for Pricing
View Details
Human FANCI activation kit by CRISPRa
GA110613 1 Kit

Human FANCI activation kit by CRISPRa

Sign In for Pricing
View Details