4- (Bromoacetyl) phenoxyacetic acid

4- (Bromoacetyl) phenoxyacetic acid (PTP inhibitor III) is a protein tyrosine phosphatase (PTP) inhibitor[1][2].

Product Specifications

CAS Number

[29936-81-0]

UNSPSC

12352005

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/4-bromoacetyl-phenoxyacetic-acid.html

Solubility

10 mM in DMSO

Smiles

O=C(O)COC1=CC=C(C(CBr)=O)C=C1

Molecular Formula

C10H9BrO4

Molecular Weight

273.08

References & Citations

[1]Saraswati S, et al. Phloretin attenuates STAT-3 activity and overcomes sorafenib resistance targeting SHP-1-mediated inhibition of STAT3 and Akt/VEGFR2 pathway in hepatocellular carcinoma. Cell Commun Signal. 2019 Oct 16;17 (1) :127.|[2]SIRPα deficient macrophages for treating cancer. World Intellectual Property Organization, .WO2023076813 A1 2023-05-04.