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8-iso-15-keto Prostaglandin F2α

Selected Variant

HY-125626

Size: 1 Each

8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a partial agonist for Thromboxane receptor (TP), which exhibits a vasoconstrictor efficacy with a pD2 of 5.8. 8-iso-15-keto Prostaglandin F2α mediates a weak relaxation of rats aorta rings at high concentration[1].

Product Specifications

CAS Number

191919-01-4

Product Name Alternative

8-iso-15-keto PGF2α

UNSPSC

12352211

Hazard Statement

H225-H319-H336-H360

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/8-iso-15-keto-prostaglandin-f2α.html

Solubility

10 mM in DMSO

Smiles

OC(CCC/C=C\C[C@H]1[C@H]([C@@H](C[C@@H]1O)O)/C=C/C(CCCCC)=O)=O

Molecular Formula

C20H32O5

Molecular Weight

352.47

Precautions

P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P370+P378-P403+P233-P403+P235-P405-P501

References & Citations

[1]Cracowski JL, et al., Response of rat thoracic aorta to F (2) -isoprostane metabolites. J Cardiovasc Pharmacol. 2002 Mar;39 (3) :396-403.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

FP

Price

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