8-iso-15-keto Prostaglandin F2α
8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a partial agonist for Thromboxane receptor (TP), which exhibits a vasoconstrictor efficacy with a pD2 of 5.8. 8-iso-15-keto Prostaglandin F2α mediates a weak relaxation of rats aorta rings at high concentration[1].
Product Specifications
CAS Number
[191919-01-4]
Product Name Alternative
8-iso-15-keto PGF2α
UNSPSC
12352211
Hazard Statement
H225-H319-H336-H360
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/8-iso-15-keto-prostaglandin-f2α.html
Solubility
10 mM in DMSO
Smiles
OC(CCC/C=C\C[C@H]1[C@H]([C@@H](C[C@@H]1O)O)/C=C/C(CCCCC)=O)=O
Molecular Formula
C20H32O5
Molecular Weight
352.47
Precautions
P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P370+P378-P403+P233-P403+P235-P405-P501
References & Citations
[1]Cracowski JL, et al., Response of rat thoracic aorta to F (2) -isoprostane metabolites. J Cardiovasc Pharmacol. 2002 Mar;39 (3) :396-403.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
FP
Explore Other Products
Browse additional items from our catalog
Recombinant Rat Inactive dipeptidyl peptidase 10 (Dpp10), partial
