Rhodady C10

Rhodady C10 (Compound C10) is a dynamin I GTPase inhibitor. Rhodady C10 blocks receptor-mediated endocytosis (IC50: 7 μM) . Dynamin is involved in clathrin-independent endocytosis, phagocytosis, and caveolae internalization[1].

Product Specifications

CAS Number

[1367579-04-1]

UNSPSC

12352005

Target

Dynamin

Type

Reference compound

Related Pathways

Cytoskeleton

Applications

COVID-19-immunoregulation

Field of Research

Infection; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rhodady-c10.html

Smiles

O=C1/C(SC(N1CC)=S)=C/C2=CC=C(C=C2)OCCCN(C)C

Molecular Formula

C17H22N2O2S2

Molecular Weight

350.50

References & Citations

[1]Robertson MJ, et al. The Rhodadyns, a New Class of Small Molecule Inhibitors of Dynamin GTPase Activity. ACS Med Chem Lett. 2012 Mar 26;3 (5) :352-6.