Acopafant
Acopafant (Dacopafant; RP 55778) is a potent platelet-activating factor antagonist. Acopafant inhibits the induction of human immunodeficiency virus (HIV) expression in chronically infected cells. Acopafant has the potential for the research of HIV infection[1].
Product Specifications
CAS Number
125372-33-0
Product Name Alternative
Dacopafant; RP 55778
UNSPSC
12352005
Target
HIV; Platelet-activating Factor Receptor (PAFR)
Type
Reference compound
Related Pathways
Anti-infection; GPCR/G Protein
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/acopafant.html
Smiles
NC(C1=C2N(C=C1)[C@@H](C3=CN=CC=C3)SC2)=O
Molecular Formula
C12H11N3OS
Molecular Weight
245.30
References & Citations
[1]Weissman D, . A platelet-activating factor antagonist, RP 55778, inhibits cytokine-dependent induction of human immunodeficiency virus expression in chronically infected promonocytic cells. Proc Natl Acad Sci U S A. 1993 Mar 15;90 (6) :2537-41.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
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