SID 26681509 (quarterhydrate)
SID 26681509 quarterhydrate is a potent, reversible, competitive, and selective inhibitor of human cathepsin L with an IC50 of 56 nM. SID 26681509 quarterhydrate inhibits in vitro propagation of malaria parasite Plasmodium falciparum and inhibits Leishmania major with IC50s of 15.4 μM and 12.5 μM, respectively. SID 26681509 quarterhydrate shows no inhibitory activity against cathepsin G[1].
Product Specifications
UNSPSC
12352005
Target
Cathepsin; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/sid-26681509-quarterhydrate.html
Purity
98.02
Solubility
DMSO : 50 mg/mL (ultrasonic) |Ethanol : 5 mg/mL (ultrasonic; warming)
Smiles
O=C(NNC(SCC(NC1=CC=CC=C1CC)=O)=O)[C@H](CC2=CNC3=CC=CC=C23)NC(OC(C)(C)C)=O.[1/4].O
Molecular Formula
C27H33N5O5S.1/4H2O
Molecular Weight
544.16
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cathepsin L; Leishmania; Plasmodium
Citation 01
Available Sizes
Frequently Asked Questions
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